Found 25 matching trials
KRAS Neoantigen Nanovaccine as Adjuvant Therapy for Colorectal Cancer/Pancreatic Cancer PHASE1 This clinical trial will utilize a neoantigen nanovaccine constructed from ...
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Nanjing Drum Tower Hospital Affiliated to Medical School of Nanjing University
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KRAS-Targeted Vaccine With Chemoimmunotherapy, Nivolumab and Ipilimumab for Patients With NSCLC PHASE1 This is a single institution, Phase 1 study for patients with Stage III/IV ...
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Johns Hopkins University
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A Study of mRNA-5671/V941 as Monotherapy and in Combination With Pembrolizumab (V941-001) PHASE1 This study will determine the safety and tolerability and establish a preli...
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Banner MD Anderson Cancer Center ( Site 1008)
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Anti-CD38 Antibody With KRAS Vaccine and Anti-PD-1 Antibody in Subjects With Pancreatic Ductal Adenocarcinoma and Refractory Non-Small Cell Lung Cancer PHASE2 The goal of this clinical trial is to test the safety and tolerability of a...
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Active Not Recruiting
Location
Georgetown Lombardi Comprehensive Cancer Center
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CAR-DC Vaccine and ICIs in Local Advanced/Metastatic Solid Tumors PHASE1 This is a pilot clinical trial for subjects with local advanced/metastatic ...
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Active Not Recruiting
Location
Biotherapeutic Department of Chinsese PLA Gereral Hospital
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Application of KRAS Vaccine in the Treatment of KRAS-mutated Malignancies PHASE1 The goal of this study is to evaluate the safety and efficacy of mRNA vacci...
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West China Hospital, Sichuan University
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Comparing Neoadjuvant/Adjuvant GVAX vs a mKRASvax Given With Anti-PD-1 and Anti-CD137 for Surgically Resectable Pancreatic Cancer PHASE1 The purpose of this study is to determine the optimal dose of AGEN2373 that...
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Johns Hopkins Sidney Kimmel Comprehensive Cancer Center
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Study of KRAS-Specific Vaccine in Patients With KRAS-Mutated Solid Tumors NA The purpose of this study is to evaluate the safety, immunogenicity and pre...
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Multiple Locations
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CIMAvax-EGF With KRAS G12C Inhibitor for the Treatment of Advanced, KRAS G12C Mutated Non Small Cell Lung Cancer PHASE2 This phase II trial tests how well giving CIMAvax-EGF with KRAS G12C inhibi...
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Roswell Park Cancer Institute
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KRAS-Targeted Vaccine Combined With Balstilimab and Botensilimab for Patients With Stage IV MMR-p Colorectal Cancer and Pancreatic Ductal Cancer PHASE1 Phase 1b study evaluating the efficacy and immune response to a synthetic l...
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Sidney Kimmel Comprehensive Cancer Center
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